Corporate Responsibility Governance and Accountability\n\nWe have proudly built a corporate responsibility (CR) governance structure that formalizes our commitment to a sustainably run business. Our Board of Directors provides strategic oversight of our CR program and environmental, social and governance (ESG) matters through the Nominating and Governance Committee.\n\nThe Cytokinetics Corporate Responsibility Committee — chaired by our Senior Vice President of Corporate Affairs — includes functional leaders and subject matter experts from across the company including Human Resources; Legal; Medical and Clinical; Facilities; Commercial; Compliance; Patient Advocacy; Chemistry, Manufacturing and Controls (CMC) and Supply Chain; Regulatory; and Research and Development (R&D). The CR Committee provides regular updates to the CEO and Board about our progress towards our corporate responsibility goals and overall strategy.\n\nTo inform our corporate responsibility planning and disclosures, we look to our stakeholders and third-party frameworks, including the Sustainability Accounting Standards Board (SASB) guidelines for our industry. We have included a reconciliation with SASB at the end of this report.